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Entry 346Filed under Breeding

Puppy Vaccine and Deworming Schedule: What to Expect

Puppies need repeated core vaccines and early parasite care. Learn the usual timing, what depends on risk or local law, and when to ask a vet.
4-minute read By Animalso Team
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Puppies need a series of vaccines—not a single visit—and parasite treatment that starts in early life. In the U.S., the American Animal Hospital Association (AAHA) recommends at least three doses of core combination vaccine between 6 and 16 weeks, while the Companion Animal Parasite Council (CAPC) recommends beginning puppy deworming at 2 weeks. Your veterinarian should tailor the plan to your puppy’s records, health, location, exposure, product labels, and local rabies law.

What is the usual puppy vaccine schedule?

AAHA’s schedule for puppies 16 weeks and younger calls for at least three doses of the core combination vaccine between 6 and 16 weeks, spaced 2–4 weeks apart. The combination covers canine distemper, adenovirus, and parvovirus; parainfluenza may also be included. The parvovirus guidance gives 6–8 weeks as the minimum starting age for the primary puppy protocol. Because maternal antibodies can interfere with vaccination, completing the series matters.

AAHA’s guideline page, originally published in 2022 and updated in 2024 to include leptospirosis as a core recommendation for all dogs, also lists a separate leptospirosis series: two doses of a four-serovar killed vaccine, starting at 12 weeks and spaced 2–4 weeks apart. Follow the specific product label and your veterinarian’s plan.

Vaccine Initial puppy protocol in AAHA guidance Follow-up in AAHA guidance
Distemper, adenovirus, parvovirus combination (parainfluenza may be included) At least 3 doses between 6 and 16 weeks, 2–4 weeks apart First-year booster within 1 year after the last initial-series dose; then boosters at 3-year intervals as indicated in the schedule
Leptospirosis 2 doses starting at 12 weeks, 2–4 weeks apart Annual boosters after the initial series
Rabies As required by law; a universal age or interval is not specified here Follow local legal requirements

These are AAHA guideline recommendations, not a substitute for a clinician’s decision or the vaccine label. See AAHA’s vaccine schedule and its canine parvovirus guidance.

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Which additional vaccines might a puppy need?

Some vaccines are selected according to the dog’s lifestyle, geographic area, and likely exposure rather than given routinely to every dog. AAHA lists Lyme, Bordetella, canine influenza, and Western diamondback rattlesnake toxoid as noncore examples.

  • Lyme and canine influenza: AAHA’s table lists two initial doses 2–4 weeks apart, followed by a dose within a year and annual boosters.
  • Bordetella: The schedule depends on formulation and route. The table includes single-dose intranasal or oral protocols and a two-dose injectable protocol.
  • Other exposure-based vaccines: Discuss whether local disease risk or your puppy’s activities make them appropriate.

AAHA describes its recommendations as discretionary guidance, not an exclusive protocol, and says clinicians should account for the individual dog and the specific vaccine instructions. Its executive summary offers the rule of thumb, “When in doubt, vaccinate,” within that patient-specific context. Read AAHA’s executive summary.

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  • Essential for Pet Owners:Designed for veterinary clinics and pet owners, these puppy vaccination record books make tracking key health details—like shots, checkups, and treatments—simple and organized. When you’re away and leave your pup with a sitter or family, the dog medical record and vaccine book serves as a quick reference for their medical history, ensuring care stays on track even in your absence. Plus, dedicated sections for photos, physical markings, and ID info prepare you for emergencies, helping you recover your friend quickly if they ever get lost.

When should puppies be dewormed?

CAPC’s general guidance recommends starting anthelmintic treatment at 2 weeks of age and repeating it every 2 weeks until regular broad-spectrum parasite control begins. CAPC recommends year-round broad-spectrum control, with a veterinarian choosing the appropriate product.

If continuous year-round control cannot be maintained, CAPC describes a fallback schedule: treat every 2 weeks until 2 months of age, monthly until 6 months, and quarterly thereafter. This is general guidance, not a direction to give a particular medicine; product age and weight limits and parasite coverage vary.

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CAPC’s hookworm guidance gives a more specific schedule for puppies and their dams: treatment when puppies are 2, 4, 6, and 8 weeks old. If treatment begins at 6–8 weeks or later, CAPC advises a monthly preventive according to label directions, another deworming in two weeks, and monthly prevention thereafter. Your veterinarian can reconcile these recommendations with the puppy’s age, previous treatments, and product label.

How often should a puppy have a fecal test?

CAPC recommends fecal examinations at least four times in the first year of life. The frequency can be adjusted for health, environmental exposure, and lifestyle. Depending on the clinical situation, testing methods may include fecal flotation, antigen testing, PCR, or AI. CAPC’s hookworm guidance separately describes fecal examinations 2–4 times in the first year to monitor treatment and prevention; your veterinarian can set a schedule suitable for your puppy.

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  • Product Include:When you choose our dog vaccines records tracker, you'll receive one notebook.This 12-page puppy health journal has 8 dedicated pages for tracking your pup’s health, vet visits, and key details, with 4 blank pages at the end for jotting down extra notes, pet-related info, or anything else you want to record.
  • Ideal Size for Record Keeping:Each dog vaccine record book measures 5x3.5 inches folded; 5x7 inches unfolded, allowing for easy portability and storage.These handy health records notebook for dogs with double sided printing, featuring enough space for all your pets important information,plus, it has dedicated spots for sticking on vaccine stickers and adding cute puppy photos.They offer a stylish and organized approach to pet health documentation, a must have addition to your pet supplies.
  • Premium Quality: The puppy health record tracker’s cover features 300gsm coated paper with vibrant full-color printing and a protective laminate finish. Inside, 100gsm high-quality offset paper pages are durable and ink-resistant, ensuring no bleeding from pens or markers—so your records stay neat and easy to read.
  • Effortlessly Track Vaccinations and More:The canine health record booklets pages include:owner and puppy information,medical history and hospitalizations,vaccination record and sticker,dog service providers,fecal examinations and de-worming,heartworm screening, prevention and treatment etc.This record keeping tool will ensure every important detail is accounted for and make this task easy, organized, and straightforward.Add this essential tool to your pet supplies for a happier, healthier pet.
  • Essential for Pet Owners:Designed for veterinary clinics and pet owners, these puppy vaccination record books make tracking key health details—like shots, checkups—simple and organized. When you’re away and leave your pup with a sitter or family, the dog medical record and vaccine book serves as a quick reference for their medical history. Plus, dedicated sections for photos, physical markings, and ID info prepare you for emergencies, helping you recover your friend quickly if they get lost.

A negative fecal test does not always rule out a concerning infection. Hookworms can cause severe illness, including anemia, and illness may develop before eggs appear in feces. Contact a veterinarian promptly if a puppy has diarrhea, vomiting, weakness, pale gums, poor growth, visible worms, or known parasite exposure.

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How to plan your puppy’s visits

  1. Bring the records you have. Share the puppy’s birth date, vaccine and deworming history, any breeder or shelter paperwork, and information about symptoms or exposures.
  2. Ask the veterinarian to map the vaccine series. Confirm which core and risk-based vaccines are appropriate, when each dose is due, and how local rabies law applies.
  3. Agree on parasite prevention and testing. Ask which product fits the puppy’s age, weight, and likely parasites, when to start it, and when to bring a fecal sample.
  4. Keep the plan current as the puppy grows. Report changes in health or exposure and follow the clinician’s schedule and each product’s label.

AAHA guidance is available at its canine vaccination guideline page. CAPC’s recommendations are in General Guidelines for Dogs and Cats and its Hookworms guidance.

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Puppy Shot Record Cards, 5x3.5 Inch Tri-Fold Vaccination Health Log for Dogs, 5 Pack, Ink-Resistant Paper, for Breeders, Vets, Pet Owners (5)
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Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Amazon at the time of purchase will apply.

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