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Entry 109Filed under Breeding

Brain Tumors in Cats: Causes, Symptoms, and Treatment

A practical guide to feline brain tumors: primary versus secondary growths, common types, warning signs, the diagnostic workflow from exam to MRI or CT and tissue testing, and the treatment options owners should discuss with a veterinary specialist.
7-minute read By Animalso Team
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“Brain tumor” is a practical umbrella term for an abnormal growth inside a cat’s skull. It covers growths that start in the brain, its lining, or nearby structures, as well as cancers that spread to the brain from another part of the body. Signs depend heavily on where the growth sits. Confirming what it is usually takes a veterinary neurologic exam, advanced imaging, and sometimes tissue testing. A seizure or new neurologic change is a reason to see a veterinarian promptly, but it does not by itself mean a tumor is present.

What “brain tumor” means in a cat

Veterinarians use the phrase to describe any intracranial mass that behaves like a neoplasm, but the category splits into two groups that matter for treatment planning:

  • Primary tumors arise within or around the central nervous system (CNS), meaning the brain, its coverings, or the structures that support it.
  • Secondary tumors start in another organ and spread to the brain. Their treatment is shaped by the original cancer as well as by the brain lesion.

Not every brain mass is cancer. Non-neoplastic space-occupying lesions can look like tumors on CT or MRI, which is why imaging findings need interpretation alongside the cat’s history and examination. A clinical review of advanced diagnostic techniques in feline brain disease, published on PubMed Central, makes this point directly.

Types of brain tumors in cats

A 2023 review of primary feline CNS neoplasms by Daniel R. Rissi in Veterinary Pathology reports that meningioma and glioma make up the majority of primary feline CNS tumors described in the veterinary literature. Other, less common or rare types are also reported. The NC State College of Veterinary Medicine neurology service lists meningioma, glioma, choroid plexus papilloma, pituitary adenoma or adenocarcinoma, and other types among primary brain tumors in dogs and cats.

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Meningioma

Meningiomas arise from the membranes that surround the brain. They are counted as brain tumors because of their intracranial location and the effects they have on the brain. As they grow, they can compress or invade nearby tissue, so their signs often reflect pressure on the adjacent brain rather than damage to a single function.

Glioma

Gliomas arise from the supportive glial cells of the brain. Like meningiomas, they are among the most frequently described primary feline tumors, and their signs depend on which part of the brain they affect.

Less common primary types

Choroid plexus papilloma, pituitary adenoma or adenocarcinoma, and other rarer tumors are described in dogs and cats. Because they are uncommon, individual case reports rather than large series usually describe them, and their behavior varies with type and location.

Causes and risk factors

The evidence reviewed here classifies brain tumors by where they start. It does not establish a specific general cause for feline brain tumors in an individual cat, and it does not provide a reliable list of risk factors. Age, breed, sex, and environmental exposures should not be presented as proven causes. Older cats do appear among reported cases, but that observation from small case series is not a population-level estimate and does not show what caused any particular tumor.

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For an owner, the practical question is rarely “why did this happen?” It is usually “what is causing these signs, and what can be done?” That question is answered through diagnosis, not through guessing at a cause.

Symptoms and when to act

The brain is organized by function, so the signs of a tumor depend on which region is affected and how much it presses on surrounding tissue. Possible changes include:

  • Seizures
  • Altered behavior, alertness, or responsiveness
  • Impaired vision, such as bumping into objects or appearing unable to see
  • Weakness or loss of coordination
  • Balance problems, circling, or a head tilt
  • Other focal neurologic deficits, meaning problems confined to one side or one area of the nervous system

Many of these signs also occur with conditions other than tumors, including inflammatory and infectious disease, vascular events, and metabolic problems. A tumor is one possibility among several differentials.

Seizures in older cats

The NC State neurology page notes that when a dog or cat older than five or six years has new-onset seizures, a brain tumor is a possible differential that a full diagnostic workup should evaluate or rule out. That guidance does not mean every seizure in an older cat is a tumor. It means the seizure should be investigated rather than assumed to be benign.

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When to seek emergency care

Contact a veterinarian promptly for any new or worsening neurologic sign. Treat the following as urgent and seek emergency evaluation:

  • A seizure that lasts a long time or repeats without the cat recovering in between
  • Collapse
  • Severe difficulty walking or standing
  • Rapid decline in alertness, vision, or coordination over hours to days

No single universal threshold applies to every cat. When in doubt, call your veterinarian or nearest emergency clinic rather than waiting to see whether the signs settle.

How a veterinarian diagnoses a suspected brain tumor

Diagnosis is a sequence. Each step narrows the possibilities and decides whether the next step is needed.

  1. History and neurologic examination. The veterinarian documents when the signs started, how they have progressed, and which neurologic functions are affected. This exam helps localize the problem within the nervous system.
  2. Screening for disease elsewhere. In suspected or diagnosed brain tumor cases, NC State recommends thoracic radiographs (chest X-rays) and sometimes abdominal ultrasound to look for cancer in other organs.
  3. Advanced imaging. MRI or CT can identify a mass and characterize its location and appearance. Other tests may look for alternative causes of the signs, such as infection or inflammation.
  4. Tissue diagnosis when needed. Histopathology from biopsy or surgical excision provides definitive typing. Whether it is needed depends on the case and on whether the result would change the treatment plan.

What MRI can and cannot show

In a retrospective 2004 study by Troxel and colleagues in the Journal of Veterinary Internal Medicine, MRI detected the tumor in 45 of 46 cats (98%) with histologically confirmed brain tumors. Two blinded, independent reviewers correctly identified tumor type from the MRI appearance in 82% of cases. These figures come from that study cohort at a particular time and do not guarantee the same performance at every clinic or for every patient. The study is available through Oxford Academic.

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Imaging is therefore powerful but not the same as a confirmed diagnosis. A scan can suggest a tumor type, while a biopsy or excision result is what establishes it.

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Treatment options

NC State describes four broad approaches: surgery, radiation therapy, chemotherapy, and palliative management of symptoms. Which one, or which combination, is appropriate depends on several factors that a veterinarian and specialist must weigh together.

Surgery

Surgery may be considered when the tumor’s location allows safe access and removal. Whether it is feasible depends on the tumor’s position relative to critical brain tissue, and the procedure is typically performed by a surgical specialist with neurologic training.

Radiation therapy

Radiation therapy uses targeted doses to reduce or control tumor growth. It is delivered through specialized veterinary centers, and the schedule and number of visits are part of the burden to weigh.

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Chemotherapy

Chemotherapy is an option for some tumor types and situations. Its suitability depends on the tumor type and on the cat’s overall health. Drug choice and dosing belong to a veterinary oncologist.

Palliative symptom management

Palliative care focuses on comfort and on controlling signs such as seizures, pain, or behavioral changes. It can be used alone or alongside other treatments. Medication for seizures or other symptoms should always be prescribed and adjusted by a veterinarian. Home remedies do not shrink a tumor and should not replace veterinary care.

Choosing among options

No single treatment is ranked best for every cat. The table below lists the questions that shape the decision. Work through them with a veterinary neurologist or oncologist.

Decision factor Questions to ask your veterinary team
Diagnostic certainty Has the tumor type been confirmed by tissue testing, or is it a suspicion based on imaging? Does the plan depend on confirmation?
Location and surgical access Can the tumor be reached safely? What functions could be affected by removal?
Symptom control and treatment burden How well can the signs be controlled? How many procedures, visits, or medications will be involved?
Access, cost, travel, and quality of life Is a specialist within reach? What is the cat’s day-to-day comfort likely to look like under each option?
Treatment goal Is the plan aimed at a longer-term control of the disease, or primarily at comfort?

Prognosis

Prognosis depends on the tumor type, its location, the cat’s overall condition, and which treatments are realistically available. Published outcome data are limited. The 2023 review by Rissi notes that comprehensive clinical outcome studies of canine and feline CNS neoplasms have not been carried out to the same standard as for some other cancers, partly because many affected animals are euthanized after diagnosis. For that reason, no reliable general survival figure applies to a cat with a brain tumor. Your veterinary team can give a prognosis for your cat’s specific situation, and they can explain what to expect with and without treatment.

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Next steps for owners

  • Record when signs began, how often seizures occur, and any video of an episode to show your veterinarian.
  • Ask whether screening for disease elsewhere, such as chest radiographs, is part of the plan.
  • Ask whether referral to a veterinary neurologist or neurosurgeon is appropriate.
  • Ask which outcomes the team would consider a good result for your cat, and what the plan is if the signs change.

The NC State neurology page on brain tumors in dogs and cats provides further background for discussions with your veterinary team.

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