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Pyometra is a bacterial infection of the uterus that can become life-threatening in an unspayed cat. If she is unwell and pyometra is possible, call your veterinarian or an emergency clinic now; do not wait for vaginal discharge, because some cats have none.
What pyometra is and why it happens
Pyometra is an infection in the uterus associated with hormonal changes in unspayed female cats. It is less common in cats than in dogs, but it is still a serious condition that needs veterinary care. The cervix—the opening between the uterus and vagina—may be open or closed, affecting what an owner can see. Merck Veterinary Manual explains the two presentations.
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Open-cervix pyometra
When the cervix is open, pus, sometimes mixed with blood, may drain from the vagina. A cat may groom herself and remove or conceal the discharge, so its absence from bedding or fur does not rule out infection.
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When the cervix is closed, infected material cannot drain normally. The uterus may enlarge and the abdomen may look swollen, but there may be no visible discharge. This form can be especially difficult for an owner to recognize by sight.
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Signs to watch for—and when to call
Possible signs include lethargy, reduced appetite, increased thirst and urination, vomiting, vaginal discharge, and abdominal enlargement. A severely ill cat may become weak or collapse. These signs can have other causes, so they cannot confirm pyometra at home; however, an unspayed cat who is ill needs prompt veterinary assessment.
- Call a veterinarian or emergency clinic now if your unspayed cat is unwell and pyometra may be possible.
- Do not wait for discharge to appear: closed-cervix disease may produce none, and an open-cervix cat may groom it away.
- If she is weak or collapses, treat the situation as an emergency and contact an emergency veterinary clinic immediately.
Pyometra can progress rapidly to shock and death. The University of Illinois College of Veterinary Medicine describes it as a potentially fatal uterine infection.
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How veterinarians diagnose pyometra
A veterinarian considers the cat’s history and physical examination, then may use abdominal X-rays or ultrasound and laboratory or blood tests. Imaging can help assess the uterus; blood testing helps evaluate the cat’s overall condition and readiness for anesthesia. These findings also help distinguish pyometra from other causes of illness or uterine enlargement. Diagnosis requires veterinary assessment, not an owner’s inspection alone. See the Merck Veterinary Manual overview of diagnosis and treatment.
How pyometra is treated
Surgery is preferred in most cases
The usual treatment is an ovariohysterectomy: surgical removal of the ovaries and uterus. This removes the infected organ. Depending on how sick the cat is, the veterinary team may first stabilize her with intravenous fluids and antibiotics, then proceed with surgery. The exact plan depends on her condition. The American College of Veterinary Surgeons outlines treatment and recovery considerations.
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Medical treatment is a selective option
Veterinarians may consider medical management in selected cases, particularly when preserving breeding potential matters and the cat’s condition and disease presentation make it appropriate. It requires veterinary-administered medication, carries risks and side effects, and recurrence is common. It is not an equivalent routine substitute for surgery, and medication should not be attempted at home. The decision belongs to the veterinarian assessing the individual cat.
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After surgery, follow the treating veterinary team’s discharge instructions, which should reflect the patient’s needs. ACVS describes restricting normal play, stairs, and off-leash activity during the first two weeks and protecting the incision from self-trauma. A veterinarian may recommend a recovery cone or suit to prevent licking or chewing; these are incision-protection aids, not treatments for pyometra. PetMD’s veterinary-authored overview also discusses post-operative care.
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Spaying before pyometra develops prevents the usual uterine form of the disease. Discuss the timing and surgical decision for your cat with your veterinarian. Merck Veterinary Manual and ACVS describe prevention and treatment.
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