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One free scan finds every outdated or missing driver and matches the right update for your exact hardware.Free scan · exact hardware matchIf an animal bit or scratched you and broke the skin, or its saliva may have reached a wound or a mucous membrane, you need a medical rabies assessment that day. Do not wait for symptoms. Whether you need rabies shots depends on the animal, how the contact happened, and your vaccination history, and a health official familiar with rabies makes that call. Rabies is almost always fatal once symptoms begin, but it is preventable when post-exposure care starts in time.
What to do in the first minutes after a bite or scratch
- Wash the wound now. Rinse it under running water and clean it with soap and water, scrubbing gently for about 15 minutes. Do not delay washing to look for supplies or to identify the animal.
- Irrigate with a virucidal agent if one is on hand. CDC suggests povidone-iodine solution. Use it after washing, not instead of washing.
- Call a healthcare provider the same day. Tell them the animal’s species, whether you were bitten or scratched, and whether you have had rabies vaccine before.
- Contact your local or state health department. CDC’s public guidance on rabies prevention (July 1, 2025) states: “If you’ve been exposed to an animal that might have rabies, contact your health department immediately.”
- Record what you can, safely. Note the animal’s species, size, color, where it went, and whether it has an owner. Do not try to capture or handle a wild animal yourself.
How the risk decision is made
CDC says a health official familiar with rabies should conduct the risk assessment. The animal’s appearance is not a reliable guide on its own. The assessment weighs the species, the animal’s behavior, the circumstances of the contact, and whether the animal can be tested or kept under observation. CDC identifies bats, skunks, raccoons, and foxes among the animals most often found with rabies in the United States, but any mammal can become infected.
Severe exposures, such as multiple bite wounds or bites to the head or neck, may need immediate consultation with public-health authorities. Do not postpone that call while you try to find out whether the animal was vaccinated.
Dogs, cats, and ferrets
When a domestic dog, cat, or ferret that bit you is healthy, available, and can be kept under observation, public-health officials often choose a 10-day observation period rather than starting post-exposure treatment straight away. If the animal stays healthy for the full period, it was not carrying rabies virus at the time it bit you. If it develops signs of rabies or dies, it is tested. Whether observation is an option depends on local rules, so follow the health department’s instructions rather than assuming it applies to your case.
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Wild animals and bats
Wild animals generally cannot be observed. They are usually euthanized and tested, and post-exposure treatment is commonly started while the results are pending. Bats need particular caution because their bites can be tiny or unnoticed, including by people who are asleep. If a bat was found in a room with a sleeping person, a young child, or someone who cannot report contact, contact the health department even without a visible bite.
Post-exposure prophylaxis (PEP) in the United States
U.S. post-exposure prophylaxis (PEP) combines three elements: wound care, rabies immune globulin (HRIG), and rabies vaccine. CDC’s current clinical guidance, updated September 10, 2026, sets the schedule according to whether you have been vaccinated before. Schedules outside the United States can differ; see the WHO section below.
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If you have not previously been vaccinated
- Wound care, plus one dose of HRIG at the start of PEP. Infiltrate HRIG around the wound where possible, and give any remaining volume at a separate site.
- Vaccine doses on days 0, 3, 7, and 14.
- People with immune disorders receive a fifth vaccine dose on day 28.
- HRIG and the first vaccine dose must never be given in the same syringe or at the same anatomical site.
If you have previously been vaccinated
CDC’s PEP guidance calls for two vaccine doses three days apart (days 0 and 3) and no HRIG. Previous vaccination is the single factor that removes the immune globulin step, so keep records of any earlier rabies vaccination and bring them to your clinic.
Pregnancy, infants, and contraindications
CDC states there are no known contraindications to rabies vaccination. Pregnancy is not a contraindication to PEP, and PEP is suitable for all ages, including infants and children. These points answer eligibility questions, but the clinician still decides the regimen for each person.
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Missed or late doses
CDC’s PEP calculator is a clinician-facing tool that generates and evaluates schedules based on ACIP recommendations. Clinicians enter the actual administration dates. If you miss or delay a dose, contact your clinician or health department rather than adjusting the schedule yourself. CDC warns that longer lapses may have unpredictable or negative outcomes.
Pre-exposure prophylaxis (PrEP)
Pre-exposure prophylaxis (PrEP) is rabies vaccination given before any exposure, for people at ongoing risk. CDC recommends PrEP for people who work directly with animals that could have rabies. Travelers to areas where rabies is common and access to medical care is limited may also consider it. CDC describes the ACIP schedule as two doses, with protection for up to three years. Recommendations depend on risk category and continuing exposure.
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PrEP does not replace post-exposure assessment. A vaccinated person who is bitten or scratched still needs medical evaluation, and their post-exposure regimen follows the two-dose, no-HRIG schedule described above.
PEP and PrEP at a glance
| Feature | Post-exposure prophylaxis (PEP) | Pre-exposure prophylaxis (PrEP) |
|---|---|---|
| When it is used | After a possible exposure | Before any exposure |
| Who it is for | Anyone with a possible exposure, after risk assessment | Selected higher-risk groups, such as some animal workers and some travelers |
| Components | Wound care, plus HRIG if not previously vaccinated, plus rabies vaccine | Rabies vaccine only |
| Schedule (U.S., CDC/ACIP) | Four vaccine doses (days 0, 3, 7, 14) if not previously vaccinated; two doses (days 0 and 3) if previously vaccinated | Two doses; protection for up to three years, with recommendations depending on risk category and continuing exposure |
| Medical assessment after a bite or scratch | Required; this is the assessment itself | Still required; PrEP does not replace it |
Global guidance from WHO
The World Health Organization (WHO) describes post-exposure care as three parts: washing the wound, giving human rabies vaccine, and giving rabies immune globulin or monoclonal antibodies when indicated. WHO guidance also includes intradermal administration, a route that differs from the U.S. regimen above.
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Country protocols, product availability, administration routes, and public-health systems vary. A schedule that is correct for U.S. clinicians may not match what a clinic elsewhere will do. If you are outside the United States, ask a local clinic or health authority which schedule applies.
Rabies in numbers
CDC’s September 10, 2026 statement says: “Rabies is preventable when people who have been exposed receive appropriate administration of the rabies vaccine before symptoms begin.” The figures below come from different sources and measure different things, so they should not be combined or compared directly.
| Figure | Source and date | What it measures |
|---|---|---|
| About 59,000 human rabies deaths each year worldwide | WHO fact sheet; 2024 estimate | Estimated global deaths from rabies |
| Up to 99% of human rabies cases are caused by dog-mediated transmission | WHO fact sheet; current figure | Share of global human cases linked to dogs |
| 17% more rabies-related inquiries in July–August 2026 than in July–August 2025 | CDC; 2026 | Rabies-related inquiries to CDC. This is not a 17% rise in human rabies cases. |
| About 1.4 million people in the United States seek medical care after animal contact each year | CDC September 2026 Health Alert Network advisory; annual estimate | Medical evaluation after animal contact, not confirmed rabies exposure |
| About 100,000 people in the United States receive PEP after a potential exposure each year | CDC September 2026 Health Alert Network advisory; annual estimate | Potential exposures, not bites confirmed to come from rabid animals |
The same CDC advisory reports increased reports of animal exposures and PEP during summer 2026. It stresses careful risk assessment, correct administration, and additional considerations for immunocompromised patients.
Keeping pets and people protected
- Keep dogs, cats, and ferrets current on rabies vaccination. Vaccination schedules and certificate requirements are set by state and local law, so confirm them with your veterinarian.
- Avoid contact with wild animals and unfamiliar animals, especially while traveling.
- Seek prompt medical advice after any bite, scratch, or other suspected exposure, even when the animal looks healthy.
- If your own pet has been bitten or scratched by a wild or unknown animal, contact your veterinarian and your local health department, and keep your pet away from other animals while you do.
Rabies remains one of the few diseases where a decision made in the first day after contact can prevent death. For U.S. readers, the operative guidance is CDC’s, and for everyone else, the local health authority’s.
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